| Friday, December 3, 2021 | |||
| TEAMS | TIME | LOCATION | |
| Saturday, December 4, 2021 | |||
| TEAMS | TIME | LOCATION | |
| Sunday, December 5, 2021 | |||
| TEAMS | TIME | LOCATION | |
| Monday, December 6, 2021 | |||||
| TEAMS | TIME | LOCATION | |||
| at St. Theresa Of Lisieux 57, Bayview SS 34 | 4:45 PM | St Theresa Of Lisieux CHS | |||
| at Thornlea SS 77, Milliken Mills 14 | 4:00 PM | Thornlea SS | |||
| Tuesday, December 7, 2021 | |||||||||||
| TEAMS | TIME | LOCATION | |||||||||
| at Dr. G.W. Williams 65, Huron Heights 53 | 4:45 PM | Dr G W Williams SS | |||||||||
| at Emily Carr 40, Holy Cross 36 | 4:00 PM | Emily Carr SS | |||||||||
| Sir William Mulock 89, at Keswick High School 24 | 4:45 PM | Keswick HS | |||||||||
| at Woodbridge College 52, Tommy Douglas SS 31 | 4:00 PM | Woodbridge College | |||||||||
| Wednesday, December 8, 2021 | |||||
| TEAMS | TIME | LOCATION | |||
| Richmond Green SS 49, at Cardinal Carter 34 | 4:00 PM | Cardinal Carter CHS | |||
| at Father McGivney 43, Bill Hogarth SS 38 | 4:45 PM | Father Michael McGivney CA | |||
| Thursday, December 9, 2021 | ||||||||
| TEAMS | TIME | LOCATION | ||||||
| at Maple High School 64, Father Bressani 17 | 3:30 PM | Maple HS | ||||||
| at Stouffville 42, St. Maximilian 40 | 4:00 PM | Stouffville DSS | ||||||
| Sacred Heart 95, at Sutton District 18 | 4:00 PM | Sutton DHS | ||||||